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Born in Wigan, the son of a clothing manufacturer. Educated at St John's College, Grimsargh, near Preston, and Pembroke College, Cambridge. Studied natural sciences.
Student at St George's Hospital Medical School Medical School 1895; house surgeon and house physician 1898; surgical registrar and demonstrator of anatomy 1899; assistant surgeon 1900-1905; surgeon 1905.
Consulting surgeon at the Royal Waterloo Hospital for Women and Children and the Kensington Dispensary and Children's Hospital. Private practice at 44 Brook Street, London. Examiner at Cambridge University, the Society of Apothecaries and the Court of Examiners. The first honorary secretary of the newly amalgamated Royal Society of Medicine 1907; later honorary treasurer and honorary fellow. The first honorary secretary of the Association of Surgeons of Great Britain and Ireland. Served on the Council of Medical Society of London.
Married Lilian Dorothea Lane, who died in 1921. They had one son, John, who became an archeologist and was killed in Greece in 1942. Pendlebury's second marriage was in 1935 to Mabel Webb (d.1959). Retired to Malvern. Died in Malvern 21 April 1953, aged 82.
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Royal College of Surgeons