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MRCS LRCP (1917), MA Cantab (1919), MB BChir (1921), MRCP (1922), FRCP (1929).
He was resident assistant at St George's Hospital and went on to become assistant physician there in 1927. During the First World War he was a senior physician and remained at St George's Hospital. While at St George's he was known for his biochemical research, which he conducted with St George's biochemist John Addyman Gardner, his compassion for his patients, and his overly scientific lecturing style. His research included renal disease, obesity, chronic bowel disorders, and diabetes mellitus. He established diabetic clinics at St George's Hospital and at the London Jewish Hospital and was known as one of the first physicians to treat with insulin. He also established a gastroenterological unit at Atkinson Morley's Hospital, Wimbledon in 1942. He was keenly interested in the social and psychological factors that influence health. He strongly supported St George's Hospital's move from Hyde Park Corner to Tooting and suggested several design ideas for the new hospital that were implemented. His obituary noted that all of this was achieved despite the fact that Gainsborough was Jewish at a time when few Jewish people held positions in West End hospitals.
In 1926 he married Maia Pilikowski, who died in 1939.
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Plarr's Lives of the Fellows