Educated at Merchant Taylors' school in London and Pembroke College, Cambridge; BA 1847. Student at St George's 1847.
House surgeon and registrar at St George's Hospital, assistant surgeon 1861-1867, surgeon 1867-1887, consulting surgeon 1887-1907; honorary treasurer 1894, vice-president 1904.
Assistant surgeon at the Hospital for Sick Children, Great Ormond Street 1859, surgeon 1861-1868. Chief surgeon to the Metropolitan Police. Hunterian professor of surgery and pathology at the Royal College of Surgeons 1872; examiner 1873-1883. President of the Royal Medical and Chirurgical Society of London (later merged with the Royal Society of Medicine) and various roles at the Clinical Society and the Pathological Society of London.
Published widely on surgery, including 'Treatise on the Principles and Practice of Surgery', 1875, and edited multiple editions of Gray's Anatomy.
Married to Sarah Brooksbank, no children. Retired in 1887. Died in 1907